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Methylcobalamin should not be used in patients with early hereditary optic nerve atrophy (Lebers disease)

55.8% reduction in the appearance of wrinkle volume in a randomized, double-blind trial over 8 weeks Pickart et al., PMC 2018 70% of volunteers showed visibly improved skin firmness, outperforming vitamin C and retinoic acid comparators Pickart et al., multiple publications 32.8% reduction in the visible appearance of wrinkle depth (double-blind, 8 weeks) Published cosmetic science research 40+ years of published research since GHK-Cu was first identified in human plasma in 1973 Discovered by Dr

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